These most influential Indian are the people who rules indian community and carries Indian brand into America , similarly these people contribute to Indian economy.
Here is 50 most influential Indian-Americans list
Ashok Amritraj
Bala Balachandran
Jagdish Bhagwati
Krishna Bharat
Karan Bhatia
Akeel Bilgrami
Deepak Chopra
Aswath Damodaran
Padma Desai
Vishakha Desai
Vinod Dham
Dinesh D’Souza
Atul Gawande
Anoop Gupta
Raj Gupta
Vin Gupta
Rajat Gupta
Sanjay Gupta
Ajit Jain
Rajesh Jha
Bobby Jindal
Vyomesh Joshi
Neal Katyal
Ali Akbar Khan
Prakash Khatri
Vinod Khosla
Jhumpa Lahiri
Sanjaya Malakar
Om Malik
Sonny Mehta
Zubin Mehta
Mira Nair
Sunil Nayar
Indra Nooyi
Kal Penn
C K Prahalad
V S Ramachandran
Raj Reddy
DJ Rekha
Salman Rushdie
Ravi Shankar
Ram Shriram
Amartya Sen
M Night Shyamalan
Amit Singhal
Sreenath Sreenivasan
Richard Verma
Sunita Williams
Zachariah P Zachariah
Fareed Zakaria
full story at Rediff